Anal cancer recurrence

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Due to the low incidence of anal cancer and generally high cure rates, few second-line treatment options have been evaluated in the setting of formal clinical trials. We briefly report two cases that were both found to have wild-type K-RAS, with no epidermal growth factor receptor amplification or evidence of prior persistent human papilloma virus infection. Both cases were treated with irinotecan and cetuximab with evidence of clinical benefit in the setting of a third recurrence, as well as evidence of response to other strategies employed in their management. These cases provide support for the suggestion that treatment planning in conjunction with molecular profiling may be beneficial in such uncommon clinical settings. However, for the subset of patients who do experience recurrence or metastatic disease, few second- or third-line treatment options exist.
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Stage IV Anal Cancer

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Anal Cancer: Types of Treatment | kostunlaw.com

For many people with anal cancer, treatment can remove or destroy the cancer. The end of treatment can be both stressful and exciting. For other people, the cancer might never go away completely. Some people may need to get treatments to try and help keep the cancer in check.
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Anal Cancer Recurrence

The anus is the end of the large intestine , below the rectum , through which stool solid waste leaves the body. The anus is formed partly from the outer skin layers of the body and partly from the intestine. Two ring-like muscles, called sphincter muscles, open and close the anal opening and let stool pass out of the body. Enlarge Anatomy of the lower digestive system, showing the colon and other organs. The skin around the outside of the anus is called the perianal area.
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Not only was I diagnosed with a rare form of cancer, I had a rare form of metastasis located in my bone. After surgery to remove the sacral tumor I received simultaneous chemotherapy and radiation; 2 rounds of chemo lasting 96 hours each and 7 weeks of radiation that resulted in my hospitalization for the last 2 weeks of treatment for pain control. I baffled them all when I went into remission last year; I have just passed my 1 year anniversary.
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